住院患儿合胞病毒和腺病毒感染调查

Survey of infection of respiratory syncytial virus and adenovirus infection in hospitalized children in 2009～2010

目的分析2009~2010年新疆维吾尔自治区人民医院住院呼吸道感染患儿呼吸道合胞病毒（RSV）和腺病毒（ADV）感染情况和临床特征。方法采用酶联免疫吸附试验法（ELISA）,对2009~2010年在新疆维吾尔自治区人民医院儿科住院的734例呼吸道感染患儿,进行血清RSV、ADV IgM抗体测定。根据检测结果,对RSV、ADV感染的季节,感染患儿的性别、年龄、民族、临床疾病及临床表现进行分析。结果 2009~2010年ADV和RSVIgM抗体全年都有检出,无明显季节性。ADV感染率24.5%（180/734）,RSV感染率19.3%（142/734）。除1~3岁与〉3岁组相比,两组ADV感染率有统计学差异（P〈0.05）外,ADV、RSV感染在性别、年龄、民族间以及临床表现方面均无显著差异（P均〉0.05）。结论 2009~2010年本地ADV和RSV感染全年流行,无明显季节性。儿科住院呼吸道感染患儿ADV和RSV感染临床表现方面无特殊,病原诊断需要实验室协诊。

Objective To survey the distribution and clinical features of respiratory syncytial virus（RSV）and adenovirus（ADV）in hospitalized children with respiratory tract infections in Xinjiang Uygur Autonomous Region People＇s Hospital in 2009~2010.Methods RSV and ADV IgM antibodies in serum of 734 hospitalized children were measured by ELISA method,then the clinical manifestations of different groups were analyzed by the seasons,sex,age and ethnicity.Results ADV and RSV were detected throughout the year and no seasonal flunctuation,ADV was detected in 180 cases with an infection rate of 24.5%,while RSV was detected in 142 cases（19.3%）.In addition,infection rate of ADV in age group of 1~3 years was significantly higher campared to 3-year-old group.No significant differences were noticed in infection rates of ADV and RSV in gender,age,ethnicity and clinical manifestations.Conclusion ADV and RSV were prevalent in this region throughout the year without seasonal flunctuation from 2009 to 2010.There was no specific clinical features in hospitalized children with ADV and RSV infection.