三种指标产前筛查出胎儿生长迟缓23例

Prediction of Fetal Intrauterine Growth Retardation with Three Indicators

方法:利用姐妹染色单体互换频率、B型超声、宫高及腹围三种指标综合判断产前诊断胎儿生长迟缓。目的:以提高产前诊断率及建立新的早期诊断方法。结果:姐妹染色单体互换频率产前诊断率为61.76%,B型超声为52.94%,宫高腹围为26.09%,姐妹染色单体互换频率阳性检出率为75%,孕20周前阳性检出率为76.19%,三种指标综合判断可使产前诊断率提高到82.19%。结论:多种指标判断可以提高产前诊断率。

Objective:To establish a new diagnostic method and multiple index to predict IUGR. Methods:Using the frequency of sister chromatid exchange(SCE)、B ultrasound and the fundal height and abdominat cincamference to predict IUGR and compare with the newborn birth weight. Result:The diagnostic rate of SCE is 61.76%,B Ultrasound is 52.94%,the fundal height and abdominal perimeter is 26.09%.The positive rate of SCE is 75%,the diagnostic rate of SCE in the first 20 weeks is 76.19%.The diagnostic rate is increased reaching 82.14% by the three index combining judgement. Conclusion:The frequence of SCE is a new diagnostic index to predict IUGR.Multiple indes combining judgement can increase the diagnostic value.