住院肿瘤患者细菌感染菌群分布及药敏分析

Analysis of bacteriological spectrum and antibiotic resistance inhospitalized cancer patients with infections

目的:了解住院肿瘤患者细菌感染的菌群分布状况及耐药趋势。方法:分析1997年～1998年住院恶性肿瘤患者送检标本中的细菌种类和药敏情况。结果:从临床送检的2142份标本中共检出693株细菌,居前四位的优势菌依次为假单胞菌29.58%,肠杆菌属细菌27.99%,葡萄球菌20.92%,真菌20.34%。本组细菌对青霉素、氨苄青霉素和磺胺大多耐药。阴性杆菌对新一代广谱抗生素和头孢菌素类耐药率一般均超过50%;阳性球菌除对氧氟沙星敏感外,对其它抗生素耐药率均较高。结论:对肿瘤患者必须严格控制抗生素的滥用,否则可能造成严重的后果,应当引起临床医师的高度重视。

Objective:To evaluate bacteriological spectrum of infection and its characteristics of antibiotic resistance in hospitalized cancer patients.Methods:The strains from clinical samples of cancer patients admitted from 1997 to 1998 and their resistance to antimicrobial agents were analysed.Results:693 strains consisting pseudomonas(29.34%),erterobacter(27.99%),staphylococcus(20.92%),fungus(20.34%) and so on,were isolated from 2142 samples.The strains showed quite high resistance rate to varied antibacterial agents.Conclusions:Close attention must be paid to tight control of antibiotic abuse in hospitalized cancer patients.