显微外科治疗儿童髓母细胞瘤

Mlcrosurgical Treatment of Medulloblastomas in Children (Report of 34 cases)

目的 用显微技术切除儿童髓母细胞瘤,减少手术并发症,提高术后生存质量。方法 对34例儿童髓母细胞瘤的临床资料进行分析。结果 34例均采用显微手术治疗,全切27例,次全切除4例,部分切除3例,手术死亡2例,死亡率为5.9％.获随访30例,临床治愈24例,症状改善6例,5年生存率为50％。结论 微创的显微外科技术是保证减少术后并发症,获得良好预后的关键。对于大多数患儿,建议术后辅以放疗。

Objective To evaluate the microsurgical techniques in management of children with medulloblastomas. Methods Clinical data of 34 cases with medulloblastomas were retrospectively analyzed. Results All of the patients were treated by microsurgical procedures. Of these 34 case, 27 were resected radically, 4 cases subtotally and another 3 partially resected. Two children died (5.9%) . Long term followup for 30 cases showed that 24 were clinically cured, 6 cases achieved symptomatic improvement . The 5-year survival rate was 50% . Conclusions Microinvassive surgical technigue was the key to reducing the postoperative complications and acllieving better prognosis. The authors suggested that for most children with medulloblastomas, postsurgi-cal radiotherapy should be considered.