摘要
目的 :应用去甲氧柔霉素 ( IDA)联合 Ara- C组成的 IA方案治疗难治性白血病观察其疗效。方法 :IDA5 mg/ d～ 10 mg/ d ivgtt连续 3 d,Ara- C10 0 mg/ d～ 2 0 0 mg/ d ivgtt连续 5 d为一疗程。结果 :5例难治性白血病 (急淋 4例 ,急非淋 1例 ) ,采用 IA方案治疗 1个～ 2个疗程后 ,完全缓解 3例 ,部分缓解 2例。结论 :应用 IA方案治疗难治性白血病取得较好疗效 ,主要副作用为骨髓抑制 ,粒细胞减少 ,未发现心、肝。
Objective:To observe the curative effect of the IA(Idarubicin in combination with Ara c) regimen for treatment on refractory leukemia. Methods: Both ldarubicin 5 mg～10 mg/d iv gtt for 3 days and Ara c 100 mg～200 mg/d iv gtt for 5 days continuously as one course. Results: Among 5 refractory leukimia patients (4 of acute lymphoblastic leukimia and 1 of acute nonlymphoblastic leukimia) complete remission was achieved in 3 patients and partial remission in 2 patients after 1～2 courscs of the trcatment. Conclusion:The IA regimen for treatmont of refractory leukimia is an effective therapy. the major toxic side effects encountered were marrow suppresion,neutrapenia. The toxic side effects in heart,liver and kidney were not found.
出处
《白血病》
2000年第1期17-18,共2页
