共同性外斜视眼肌的超微病理研究

Ultrastructural pathological study of ocular muscles in comitant exotropia

目的 :为研究共同性外斜视眼肌的超微病理结构。方法 :应用Hu 1 2A电子显微镜对 6例共同性外斜视的眼肌进行观察。结果 :内直肌肌纤维普遍细小 ,肌原纤维密集 ,Z带不清 ,肌原纤维排列方向错乱 ,线粒体多 ,嵴密 ,肌质网扩张 ,个别肌纤维质膜破损 ,有的有髓神经髓鞘层次不清 ,轴突旁水肿 ,外直肌部分纤维化。结论

Objective:A study on the ultrastructural changes of ocular muscles in comitant exotropia.Method:The pathological ultrastructure of ocular muscles was studied with Hu—12A transmission electron microscope in 6 specimens of comitant exotropia.Results:The muscle fibers of medial rectus became slender and myofibrils denser.Z band wasn′t clean.Arrangemental direction of myofibrils became disorderly.Mitochondria were many and mitochondrion crista became thick.Sarcoplasmic reticulum was enlarge.Individual plasma membrane of muscle fibers was broken.Levels of myelin sheath were confused in some medullated fibers of myelin sheath.The side of neurite axon became edema.Fibrosis developed in parts of lateral recturs.Conclusion:Pathological changes existed in medial rectus ultrastructural degeneration to different extent and partial lateral rectus fibrosis were the main causes of comitant exotropia.