期刊文献+

心脑佳配方对慢性酒精处理大鼠海马谷氨酸含量及NR2B表达的影响

Effect of Xinnaojia Recipe on glutamate content and NR2B expression in hippocampus of rats with chronic alcoholism
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摘要 酒精中毒是危害人类健康的杀手之一,与酒精中毒和酒精滥用相关的健康、心理和社会问题已成为当前重大的公共卫生问题之一^[1]。心脑佳配方是新乡医学院万光瑞教授自主研发的一种快速、高效、多途径抗急慢性酒精中毒的食药两用中药。
出处 《第二军医大学学报》 CAS CSCD 北大核心 2012年第1期112-114,共3页 Academic Journal of Second Military Medical University
基金 河南省教育厅自然科学研究项目(2009A310004)~~
关键词 心脑佳配方 酒精中毒 N-甲基D-天冬氨酸受体 谷氨酸 Xinnaojia Recipe alcoholism N methyl-D-aspartate receptors glutamic acid
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  • 1De Rick A,Vanheule S,Verhaeghe P.Alcohol addiction and theattachment system:an empirical study of attachment style,alex-ithymia,and psychiatric disorders in alcoholic inpatients[J].Subst Use Misuse,2009,44:99-114.
  • 2俞军龄,陈再兴,毛小元,孟秀君,郭凤,刘睿,吴坤灿,谢妮,蔡际群.HPLC法测定tremor大鼠脑组织中谷氨酸和GABA含量[J].中国药理学通报,2009,25(11):1530-1533. 被引量:19
  • 3Burke C J,Tobler P N,Baddeley M,Schultz W.Neural mecha-nisms of observational learning[J].Proc Natl Acad Sci USA,2010,107:14431-14436.
  • 4Stoneham E T,Sanders E M,Sanyal M,Dumas T C.Rules ofengagement:factors that regulate activity-dependent synapticplasticity during neural network development[J].Biol Bull,2010,219:81-99.
  • 5Li R,Huang F S,Abbas A K,Wigstrm H.Role of NMDA re-ceptor subtypes in different forms of NMDA-dependent synap-tic plasticity[J].BMC Neurosci,2007,8:55.
  • 6Mallon A P,Auberson Y P,Stone T W.Selective subunit antago-nists suggest an inhibitory relationship between NR2Band NR2A-subunit containing N-methyl-D:-aspartate receptors in hipp-ocampal slices[J].Exp Brain Res,2005,162:374-383.
  • 7Kash T L,Matthews R T,Winder D G.Alcohol inhibits NR2B-containing NMDA receptors in the ventral bed nucleus of the striaterminalis[J].Neuropsychopharmacology,2008,33:1379-1390.
  • 8Umhau J C,Momenan R,Schwandt M L,Singley E,Lifshitz M,Doty L,et al.Effect of acamprosate on magnetic resonance spec-troscopy measures of central glutamate in detoxified alcohol-dependent individuals:a randomized controlled experimentalmedicine study[J].Arch Gen Psychiatry,2010,67:1069-1077.
  • 9Wang J,Carnicella S,Phamluong K,Jeanblanc J,Ronesi J A,Chaudhri N,et al.Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum:implications foralcohol drinking behavior[J].J Neurosci,2007,27:3593-3602.
  • 10吴艳,万华印.葛根素对培养脑细胞缺氧/再给氧损伤的保护作用[J].中国药理学通报,2006,22(9):1130-1133. 被引量:2

二级参考文献18

  • 1陈杰,何明,赖仲方.氯离子对心肌细胞缺氧/复氧损伤的影响[J].中国药理学通报,2005,21(4):475-478. 被引量:10
  • 2罗璨,郭莲军.牛磺酸对大鼠急性脑缺血神经元凋亡的影响[J].中国药理学通报,2005,21(9):1057-1061. 被引量:19
  • 3Bowery N G,Smart T G. GABA and glycine as neurotransmitters:a brief history [ J ]. Br J Pharmacol, 2006,147 ( Suppl. 1 ) : S109 - 19.
  • 4Cai J Q, Ishihara K, Nagayama T, et al. Long-lasting antiepileptic effeets of levetiraeetam against epileptie seizures in the spontaneously epileptic rat(SER) :differentiation of levetiraeetam from conventional antiepileptie drugs [J]. Epliepsia, 2005,46 ( 9 ) : 1362 - 70.
  • 5Kitada K,Akimitsu T,Shigematsu Y, et al. Accumulation of N-acetyl-L-aspartate in the brain of the tremor rat, a mutant exhibiting absence-like seizure and spongiform degeneration in the central nervous system [ J ]. Neurochem,2000, Jun,74 ( 6 ) :2512 - 9.
  • 6Carlson B B,Behrstock S,Tobin A J,Salamone J D. Brain implantations of engineered GABA-releasing cells suppress tumor in an animal model of Parkinsonism [ J ]. Neuroscience, 2003,119 ( 4 ) : 927 - 32.
  • 7Shah A J, Crespi F, Heidbreder C. Amino acid neurotransmitters: separationapproaches and diagnostic value [ J ]. J Chromatogr B, 2002,781(1 -2) :151 -63.
  • 8de Freitas silva D M, Ferraz V P formance liquid chromatographic Ribeiro A M. Improved high-permethod for GABA and glutamate determination in regions of the rodent brain [ J ]. J Neurosci Methods,2009,177 (2) :289 - 93.
  • 9谈冶雄,李万亥,姜远英,陶学斌,陈卫平.Ebselen对自由基诱发的皮层神经元和皮层线粒体脂质过氧化损伤的保护作用[J].药学学报,1997,32(3):166-170. 被引量:5
  • 10熊文,王友联,李晓玫,裴瑾,杨翰仪.谷氨酸对原代培养海马神经细胞兴奋毒作用的研究[J].白求恩医科大学学报,1997,23(6):600-602. 被引量:10

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