75例骨质疏松性椎体压缩骨折的微创治疗

Mini-invasive Treatment for 75 Patients of Osteoporotic Vertebral Compression Fractures

目的评价经皮椎体成形术和经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的效果。方法 75例骨质疏松性椎体压缩性骨折患者108个椎体,在C型臂X线透视下,经皮穿刺,在病椎注入聚甲基丙烯酸甲酯。术前及术后1 d进行疼痛视觉类比评分,并进行统计学分析。同时记录骨水泥渗漏情况。结果 75例患者治疗后疼痛较治疗前有明显好转,VAS评分差异有统计学意义(P<0.01)。经皮椎体成形术组和经皮椎体后凸成形术组病例术后疼痛改善比较差异无统计学意义(P>0.05);两组平均单个椎体手术时间比较差异有统计学意义(P<0.01),经皮椎体后凸成形术组手术时间明显长于经皮椎体成形术组。结论经皮椎体成形术和经皮椎体后凸成形术属微创手术,该手术治疗骨质疏松性椎体压缩骨折止痛效果明显。

Objective To evaluate the therapeutic effect of percutaneous vertebroplasty（PVP） and percutaneous kyphoplasty（PKP） in treating osteoporotic vertebral compression fractures（OVCF）.Methods The 108 osteopomtic vertebral compression fractures in 75 patients were injected polymethymethacrylate（PMMA） with a bone marrow biopsy needle under the guidance of C-arm fluoroscopy.Visual analogue scale（VAS） was evaluated one day before and after PVP or PKP therapy,and the PMMA leakage was recorded.Results After PVP or PKP,the pain was relieved considerably in all the 75 patients.The difference was significant in VAS（P0.01）.The post-operational pain relief in PVP group and PKP group had no statistical difference（P0.05）.The average operation time for each centrum was significantly different between the two groups（P0.01）.PKP group used more time than PVP group.Conclusion PVP and PKP are both mini-invasive techniques which are effective in relieving the pain in patients with osteoporotic vertebral compression fractures.