期刊文献+

紧密连接蛋白Claudin-6和PKCθ在非典型性脑膜瘤组织中的表达 被引量:1

下载PDF
导出
摘要 非典型性脑膜瘤占成人脑膜瘤的5%~8%,其侵袭性行为导致手术后容易复发。作者前期研究表明Claudin-6表达下调可能在脑膜瘤发生和侵袭中起作用〔1〕。蛋白激酶C(PKC)作为细胞增殖、分化和凋亡过程信号转导中的磷脂依赖型蛋白激酶,在维持紧密连接(TJs)的功能中发挥重要作用。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第3期592-593,共2页 Chinese Journal of Gerontology
基金 吉林市科技局科研基金项目(200903022)
  • 相关文献

参考文献5

二级参考文献32

  • 1徐瑞明,金顺子,刘扬,刘树铮.蛋白激酶PKCθ的研究进展[J].吉林大学学报(医学版),2005,31(4):640-644. 被引量:10
  • 2Hahn HP, Bundock EA, Hornick JL, et al staining for claudin- 1 can help distinguish meningiomas from histologic mimics. Am J Clin Pathol, 2006, 125(2) :203-208.
  • 3Furuse M, Fujita K, Hiiragi T, et al. Clandin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occluding. J Cell Biol, 1998, 141 (7) :1539-1550.
  • 4Swisshelm K, Machl A, Planitzer S, et al. SEMP1, a senescence- associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily. Gene, 1999, 226(2) :285-295.
  • 5Quan C, Lu SJ. Identification of genes preferentially expressed in mammary epithelial cells of Copenhagen rat using subtractive hybrid- ization and microa-rrys. Carcinogenesis, 2003, 24 ( 10 ): 1593-1599.
  • 6Erdel M,Baier-Bittedich G,Duba C,et al G.Mapping of the huInan protein kinase C-them(PRKCQ)gene locus to the short arm of chromoeome 10(10p15)by FISH.Genomics,1995,25(2):595-597.
  • 7Hahn HP,Bundock EA,Hornick JL.Immcenhistochemieal staining for claudin-1 can help distinguish meningiomas from histologleminies.Am J Ciin Pathol,2006,125(2):203-208.
  • 8Schneeberger EE,Lynch RD.The tight junction:a multifunctional complex.Am J Physiol Cell Physiol,2004,286(6):C1213-1228.
  • 9Anderson JM,Van Itallie CM.Tight junctions and the molecular basis for regulation of paraceilular permeability.Am J Physiol,1995,269(4):G467-475.
  • 10Sedwick CE, Altman A. Perspectives on PKCθ in T cell activation Molecular [J]. Immunology, 2004, 41: 675-686.

共引文献12

同被引文献9

  • 1Shibutani M,Noda E,Maeda K,et al.Low expression of claudin-1 and presence of poorly-differentiated tumor clusters correlate with poor prognosis in colorectal cancer[J].Anticancer Res,2013,33(8):3301-3306.
  • 2Ouban A,Hamdan H,Hakam A,et al.Claudin-1 expression in squamous cell carcinomas of different organs:comparative study of cancerous tissues and normal controls[J].Int J Surg Pathol,2012,20(2):132-138.
  • 3李青,徐庆中主译.神经系统肿瘤病理学和遗传学[M].第3版,北京,人民卫生出版社,2006:206-212.
  • 4Perry A,Louis DN,Scheithauer BW,et al.World health organization classification of tumours of the central nervous system[M].4th ed Lyon:IARC,2007:164.
  • 5Yoshida T,Kinugasa T,Akagi Y,et al.Decreased expression of claudin-1 in rectal cancer:a factor for recurrence and poor prognosis[J].Anticancer Res,2011,31(7):2517-2525.
  • 6Kwon MJ.Emerging roles of claudins in human cancer[J].Int J Mol Sci,2013,14(9):18148-18180.
  • 7Stebbing J,Filipovi?觬 A,Giamas G.Claudin-1 as a promoter of EMT in hepatocellular carcinoma[J].Oncogene,2013,32(41):4871-4872.
  • 8Hahn HP,Bundock EA,Hornick JL.Immunohistochemical staining for claudin-1 can help distinguish men-ingiomas from histologic mimics[J].Am J Clin Pathol,2006,125(2):203-208.
  • 9Bezdekova M,Brychtova S,Sedlakova E,et al.Analysis of snail-1,e-cadherin and claudin-1 expression in colo-rectal adenomas and carcinomas[J].Int J Mol Sci,2012,13(2):1632-1643.

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部