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老年骨肉瘤组织中MMP-7和VEGF的表达及其意义 被引量:8

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摘要 老年骨肉瘤临床较为少见,但其临床表现的生物学行为常为进展性,即预后较差。而且新近研究表明老年骨肉瘤生长过程常依赖于血管生成,且血管生成作用明显增强〔1〕。基质金属蛋白酶(MMPs)是一大类锌依赖性内肽酶家族,在肿瘤浸润性生长和转移中起重要作用,而且参与肿瘤血管生成〔2〕。
作者 吴同申 孟彦
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第3期606-607,共2页 Chinese Journal of Gerontology
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参考文献8

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二级参考文献10

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