矽肺和石棉肺患者血清单胺氧化酶和铜蓝蛋白的对比观察

Comparative study on serum monoaminoxidase and ceruloplasmine in patients with silicosis and asbestosis.

本文测定了44例矽肺和63例石棉肺病人的血清单胺氧化酶和铜蓝蛋白的含量。结果发现,矽肺和石棉肺病人高于接尘工人,且随着病期的增高有递增趋势。另外发现血清单胺氧化酶和铜蓝蛋白的增加,两者之间有平行一致关系。血清单胺氧化酶也和血清铜蓝蛋白一样,可以用作了解肺纤维化进展情况,以及动态观察疗效的一项生化指标。

Serum monoamlnoxidase (SMAO) and ceruloplasmine (SCP) were examined in 44 cases of silicosis and 63 cases of asbestosis. The results showed that the levels of SMAO and SCP in patients with silicosis and asbestosis were higher than those in the dust exposed workers, moreover, SMAO and SCP were increased with the increase of category. In addition, the rise in SMAO level was shown to be closely paralleled with that in SCP level. Therefore, SMAO like SCP, also can be used clinically as a biochemical index to show the progression of pulmonary fibrosis, as well as to evaluate the effects of treatment.