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奥沙利铂联合5-氟尿嘧啶及亚叶酸钙治疗老年晚期大肠癌患者的临床研究 被引量:4

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摘要 结肠癌发病率在世界居恶性肿瘤第4位[1],约50%患者发生转移[2]。单用5-氟尿嘧啶(5-FU)在进展期肿瘤中其有效率大约仅为10%[3]。奥沙利铂(L-OHP)为二氨基环己烷基团铂类复合物,作用机制为抑制DNA复合物形成。单剂使用L-OHP对转移性结肠癌患者有效率可达到10%~24%[4]。
出处 《北京医学》 CAS 2012年第1期4-4,14,共2页 Beijing Medical Journal
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参考文献6

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二级参考文献9

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共引文献354

同被引文献43

  • 1赵亚恒.用奥沙利铂联合氟尿嘧啶和四氢叶酸钙治疗晚期大肠癌的疗效观察[J].求医问药(下半月刊),2012,10(12):613-614. 被引量:2
  • 2彭波.5-氟尿嘧啶联合顺铂亚叶酸钙治疗晚期消化道癌的临床观察[J].山西医药杂志,2005,34(6):501-502. 被引量:2
  • 3李悦,于雁.奥沙利铂联合氟尿嘧啶、亚叶酸钙联合治疗晚期消化道癌临床疗效分析[J].实用肿瘤学杂志,2006,20(6):525-526. 被引量:4
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