冠状动脉造影导致颅内出血12例

Report of 12 cases of Coronary angiography induced intracranial hemorrhage

目的探讨冠状动脉造影引起颅内出血的原因、临床表现和预防措施。方法回顾性分析我院收治的1332例冠状动脉造影,其中12例在造影操作过程中和其后的24 h内出现颅内出血。结果冠状动脉造影出血组与非出血组在既往房颤病史和糖尿病病史方面比较均无显著性差异,而在高血压、脑卒中、吸烟和冠心病病史方面两组间有显著性差异。术前患者血压检查非出血组平均为145.8/90.2 mmHg,出血组为165.9/105.5 mmHg,P<0.01,两组间有显著性差异。结论冠状动脉造影检查引起的颅内出血是综合因素所致,其中控制效果不好的高血压病史是引起颅内出血的重要原因,而术前和术中的血压升高是引起颅内出血的主要原因。

Objective To investigate the intracranial hemorrhage caused by coronary angiography and the clinical manifestations and preventive measures were discussed.Methods 1332 cases of coronary angiography in our hospital in nearly 2 and half years were retrospectively analyzed of which 12 cases had intracranial hemorrhage during operation and 24 hours after the procedure.Results Atrial fibrillation and diabetes mellitus in the past medical history were no statistical different between the non-hemorrhage group and the hemorrhage group.But the history of hypertension,stroke,smoking and coronary heart disease,especially the elevated blood pressure before coronary angiography,were statistically significant different between the two groups.Conclusion The intracranial hemorrhage during coronary angiography is caused by a combination of factors,but the elevated blood pressure before and during the operation are the main caused.