电脑辐射对精液活性氧含量及精子质量影响

Effects of computer electromagnetic radiation on semen reactive oxygen species and semen quantity

目的探讨电脑辐射对男性精液活性氧含量及精子质量的影响。方法 56例成年男性按照电脑使用情况分成2组:未使用电脑者为对照组,每天使用电脑>2 h者为暴露组;按照WHO标准方法对研究对象的精液常规参数、精液活性氧含量、精子顶体酶活性及精子去透明带穿卵率进行检测,并对2组的各项参数进行比较分析。结果 2组比较,电脑暴露组的精液活性氧[分别为(24.2±17.1)(、12.2±8.1)]含量升高,精子顶体酶活性[分别为(78.9±19.8)(、110.3±23.3)]和精子去透明带穿卵率[分别为(24.2±17.1)(、47.4±19.6)]降低,2组差异有统计学意义(P<0.05);电脑暴露组与对照组的精液常规参数比较,pH、精液量、精子密度、精子活率、活力、活动率差异无统计学意义(P>0.05),但精子形态正常率差异有统计学意义(P<0.05)。结论电脑辐射可使精液活性氧含量增高,改变精子形态和受精功能。

Objective To investigate the effects of computer electromagnetic radiation on reactive oxygen species（ROS） level in semen and sperm fertilization capacity of male adult.Methods Totally 56 male adults were divided into two groups according to their active computer use：control group（without computer use） and exposure group（with computer use of 2 hours per day）.The routine parameters of ROS level in semen,sperm acrosin activity,and the rate of sperm penetration of zona-free hamster egg（SPA） were detected according to WHO standards.Results The results showed an increase in ROS level in semen（24.2±17.1 vs 12.2±8.1） and decreases in sperm acrosin activity（78.9±19.8 vs 110.3±23.3） and the rate of sperm penetration of zona-free hamster egg（24.2±17.1 vs 47±19.6） in exposure group compared with those of the control（P〈0.05 for all）.The comparisons of mean semen volume,pH,sperm motility and viability between exposure and the control group showed no significant difference（P〉0.05 for all）.But the rate of sperm normal morphology was significantly different（P〈0.05）.Conclusion The results suggest that computer electromagnetic radiation may increase ROS level in semen and impair sperm morphology and fertilization capacity in male adult.