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心肌纤维母细胞的自分泌/旁分泌作用

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摘要 心肌纤维母细胞在调节正常心肌功能和干预异常心肌重塑中都起着极其重要的作用。除了合成和降解细胞外基质,心肌纤维母细胞还产生各种生物活性分子,包括细胞因子,血管活性肽和生长因子。这些生物活性分子经自分泌/旁分泌途径、信号转导途径和基因水平调控等调节机制,维持心脏正常的结构、机械、生物化学及电活动。
作者 孙苓 李一文
出处 《国际心血管病杂志》 2012年第1期36-38,共3页 International Journal of Cardiovascular Disease
基金 国家自然科学基金(81070583)
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