2010年版《中国药典》一部中活血化瘀类中药制剂分析

Review on Formulation of Traditional Chinese Medicine with Activating Blood and Removing Stasis from 〈Chinese Pharmacopoeia〉 2010

对2010年版《中国药典》一部中活血化瘀类中药制剂进行检索,对该制剂的数量、剂型、制剂处方中药材使用频次、适用病症领域、质量控制用分析方法等内容进行整理、归类和分析。药典中涉及活血化瘀的中药制剂共有148种,包括24种剂型,制剂处方中使用频次最多的前5种药材是川芎、红花、当归、丹参和三七;分析方法以薄层色谱法、高效液相法和气相色谱法为主,较好地体现了活血化瘀类中药制剂的特点、应用现状和不断提高的质量控制。分析结果能够促进药学工作者对活血化瘀中药制剂的全面认识,对该类制剂的进一步开发和应用提供较好的指导作用。但从中药现代化要求的整体水平来看,该类制剂的新剂型还偏少,药效物质含量得以确定的还不多,质量控制还不够充分,先进分析手段的应用还未全面普及,有待于进一步的提高与完善。

To review the preparation with activating blood and removing stasis from 〈Chinese Pharmacopoeia〉 2010 from 〈Chinese Pharmacopoeia〉 2010.After screening the contents of the preparation with activating blood and removing stasis in 2010 pharmacopoeia,the quantities,formulation species,herbs in pharmaceutical prescription,indications and analytical methods used for quality control were collected,classified and analyzed.148 preparations including 24 formulation were obtained.The five herbs used most were Rhizoma Chuanxiong,Flos Carthami,Angelica,Radix Salviae Miltiorrhizae and Radix Notoginseng.The methods were mainly analyzed by thin layer chromatography,high performance liquid chromatography and gas chromatography,which reflected the application status of traditional Chinese medicine with activating blood and removing stasis and quality control improved continuously.The review will help the researchers know the preparation with activating blood and removing stasis deeply and completely.Also,it will bring an instruction to the preparation's next development and application.However,from the whole level required from the mordernization of traditional Chinese medicine,the number of new formulations and effective materials determined are still less.Also,the methods suitably used for quality control are not so much and the application for advanced analytical techniques has not been used widely.They need to be improved in the further time.