摘要
总结了缓释滴丸的研究意义,对其制法进行了分类研究。目前制备工艺的研究是缓释滴丸研究的关键,通过研究各个因素对滴丸剂的成型性的影响,对缓释滴丸的制备工艺进行了考察,并且对缓释滴丸剂型存在的问题及发展概况进行了探讨。缓释滴丸较传统滴丸剂相比具有生物利用度高,毒副作用低的优点,它提高了药物的生物利用度,减少了用药次数,避免了血药浓度峰谷现象的出现,提高了病人的顺应性,在临床得到了广泛应用,由于以上优势,缓释滴丸剂型成为近年来研究的热点之一。
Through the documents,we expound the current situation of the sustained release drop pill and its technology,Summarizes the research significance of the sustained release drop pill and the method of the classification.technical research is the key of the pill.Compared to traditional drop pills,sustained release drop pill has higher bioavailability,sustained release drop pill with the advantages of bioavailability and low toxicity has become one of the impressing dosage fome.the existing problems of the sustained release drop pill is also discussed.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第3期250-252,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
缓释滴丸
制法分类
固体分散技术
制备工艺
sustained release drop pill
method of preparation
soild dispersion
preparation technology