消化性溃疡脾胃虚寒证患者治疗前后血清有关微量元素含量观测

DETERMINATION ON THE CONTENTS OF SERUM TRACE ELEMENTS IN PATIENT WITH PEPTIC ULCER BELONGLNG TO DEFICIENCY AND COLDNESS OF SPLEEN AND STOMACH

为探讨脾胃虚寒证与微量元素的关系，测试了４１例消化性溃疡脾胃虚寒证患者血清锌、铜、硅和钼的含量，与正常人相比，脾胃虚寒证患者血清锌、铜和硅含量均见降低，有显著的统计学意义，提示脾胃虚寒证的发生与微量元素含量异常有关。应用具有温阳散寒、健脾益气作用的益气祛寒养胃汤，对上述 ４１例患者进行治疗观察，总有效率达９７．５６％，痊愈率达 ７８．０５％；并随机选取 ３７例病人做治疗前后动态观察，发现治疗后随着脾胃虚寒证的改善和疾病的痊愈，患者血清微量元素失调都有不同程度地纠正，提示温阳健脾药可调整脾胃虚寒证微量元素代谢异常，亦进一步证实了脾胃虚寒证与微量元素含量异常有着内在的病理联系。

The paper reported the determination on the serum trace elements contents in patients (41 cases) with peptic ulcer belonging to deficiency and coldness of spleen and stomach syndrome,and the detemination of the changes of them in patients treated with Yiqiquhanyangwei decoc- tion.The results showed that the contents of serum Zn. Cu and Si were significant lower than that in normal. (P〈0.05 0.001) .The curative effect of Yiqiquhanyangwei decoction was obvious,the total effective rate was 97.56%,the cure rate was 78.05%,meanwhile, the disorder of serum traee elements in patient was correctted at different degree. All these suggested that warming- yang and strengthening spleen medicine could regulate the metabolism disorder of trace elements in patients with deficiency and coldness of spleen and stomach,and indicated that there was a pathologic relationship between deficiency and cold- eess of spleen and stomach syndrome and abtnormal trace elements' metabolism.