期刊文献+

PTSD大鼠模型的实验研究 被引量:1

下载PDF
导出
摘要 创伤后应激障碍(posttraumatic stress disorder,PTSD)是指受到亲身经历或目睹的异乎寻常的威胁性、灾难性事件所致的心理创伤,导致出现长期持续性精神障碍[1]。在竞争日益激烈的现代社会,应激事件日趋增多,PTSD的发生呈明显上升趋势,对PTSD的研究,可有效降低应激人群PTSD的发生,促进应激人群的身心健康。
作者 王芳
出处 《中风与神经疾病杂志》 CAS CSCD 北大核心 2012年第1期80-81,共2页 Journal of Apoplexy and Nervous Diseases
  • 相关文献

参考文献8

  • 1Li S, Murakami Y, Wang M, et al. The effects of chronic valproate and diazepam in a mouse model of posttraumatic stress disorder[ J]. Pharmacol Biochem Behav ,2006,85 (2) :324 - 331.
  • 2Yehuda R, Bierer LM, Schmeidler J. Low cortisol and risk for PTSD in adult offspring of holocaust suirivors [ J ]. Am J Psychiatry, 2000, 157(8) :1252 - 1259.
  • 3Wakizono T, Sawamura T, Shimizu K, et al. Stress vulnerabilities in an animal model of post-traumatic stress disorder[ J]. Physiol Behav, 2007,90 (4) :687 - 695.
  • 4Cohen H, Kaplan Z, Matar MA, et al. Anisomycin, a protein synthesis inhibitor, disrupts traumatic memory consolidation and attenuates posttraumatic stress response in rats [ J ]. Biol Psychiatry, 2006,60 ( 7 ) : 767 - 776.
  • 5Cohen H, Kaplan Z, Matar MA, et al. Long-lasting behavioral effects of juvenile trauma in an animal model of PTSD associated with a failure of the autonomic nervous system to recover[ J]. Eur Neuropsychopharmacol,2007,17 (6 - 7 ) :464 - 477.
  • 6Kohda K, Harada K, Kato K, et al. Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats : A putative post-traumatic stress disorder model [ J ]. Neuroscience ,2007,148 ( 1 ) :22 - 33.
  • 7Yamamoto S, Morinobu S, Fuchikami M, et al. Effects of single prolonged stress and D-cycloserine on contextual fear extinction and hippocampal NMDA receptor expression in a rat model of PTSD [ J ]. Neuropsychopharmacology,2008,33 (9) :2108 - 2116.
  • 8Liberzon I, Lopez JF, Flagel SB, et al. Differential regulation of hippocampal glucocorticoid receptors mRNA and fast feedback:relevance to post-traumatic stress disorder [ J]. J Neuroendocrinol, 1999, 11 (1):11 -17.

同被引文献7

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部