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血清CA_(125)对卵巢上皮性癌的诊断及临床分期的价值 被引量:7

The diagnostic and clinical stage value of serum CA_(125) levels in patients with epithelial ovarian cancer
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摘要 目的探讨血清CA125对卵巢上皮性癌的诊断及临床分期的价值。方法选择卵巢上皮性癌住院患者(38例)、卵巢良性肿瘤患者(38例)及卵巢子宫内膜异位囊肿患者(46例),均取空腹静脉血,用电化学发光免疫分析法测定血清CA125水平。结果血清CA125水平在卵巢上皮性癌组显著升高为(974.74±749.66)U/mL,高于卵巢良性肿瘤组的(24.73±19.95)U/mL及卵巢子宫内膜异位囊肿组的(84.05±70.51)U/mL,差异有统计学意义(P<0.05),血清CA125对卵巢上皮性癌的灵敏度为79.55%,特异度为90.63%。卵巢上皮性癌各期的血清CA125水平比较,差异有统计学意义(P<0.05),Ⅰ期最低,Ⅳ期最高。结论血清CA125水平对卵巢上皮性癌的诊断及其临床分期有重要价值。 Objective To explore the clinical value of the serum CA125 in the diagnosis and clinical stage of epithelial ovarian cancer (EOG). Methods Using the method of Electricity chemiluminescence immunoas say the levels of serum CA125 in 38 patients with EOG, 38 patients with ovarian benign tumor and 46 pa tients with ovary endometriotic cysts were measured. Results The levels of serum CAte~ of E()G patients were significantly higher than that of the ovarian tumor group and ovary endometriotic cysts group (P 0.05). The serum levels of CA125of various clinical stage of EOG patients were significantly different (P d0.05), the stage I was the lowest and the IV stage was the highest. Conclusion The serum CA125 levels play important value in the diagnosis and clinical stage of epithelial ovarian cancer.
出处 《新疆医科大学学报》 CAS 2012年第1期61-64,共4页 Journal of Xinjiang Medical University
关键词 卵巢上皮性癌 卵巢良性肿瘤 卵巢子宫内膜异位囊肿 血清CA125 epithelial ovarian cancer ovarian benign tumor ovarian endometriosis CA125
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  • 1沙玲,陶瑞,兰莉.癌相关抗原125在恶性卵巢肿瘤治疗前后的变化[J].国际检验医学杂志,2007,28(4):323-324. 被引量:3
  • 2高寒,姜军,杨新华,范林军,谢竞,周艳.5种血清标志物的不同组合对提高乳腺癌诊断的意义[J].第三军医大学学报,2007,29(12):1255-1257. 被引量:27
  • 3Adams J,Carder PJ,Downey S,et al.Vascular endothelial growth factor(VEGF)in breast cancer:comparision of plasma,serum,and tissue VEGF and microvessel density and tamoxifen[J].Cancer Res,2000,60(11):2898.
  • 4Picard A,Torres A,Maestro ML,et al.Quantitiative analysis of cyto-solic content of CEA,CA125and SCC in non-small cell lung cancer[J].Cancer,1999,73(9):2305.
  • 5Duk JM,Adlders JG,Fluren GJ,et al.CA125:a useful marker in end-ometrial carcinoma[J].Am J Obstet Gynecol,1986,155(5):1097-1102.
  • 6Ebina Y,Sakuragi N,Hareyama H,et al.Para-aortic lymph node met-astasis in relation to serum CA125levels and nuclear grade in end-ometrial carcinoma[J].Acta Obstet Gynecol Scand,2002,81(5):458-465.
  • 7Moss EL,Hollingworth J,Reynolds TM.The role of CA125in clinical practice[J].J Clin.Pathol,2005,58(3):308-312.
  • 8Ashraf MK,Ferdous A,Hossein P,et al.The role of mutationgs in core protein of hepatitis B virus in liver fibrosis[J].Virol J,2009,6(1):209-218.
  • 9Jemal A, Siegel R, Ward E, et al. Cancer statistics ,2008. CA Canc- er J C1in,2008,58(2) :71-96.
  • 10Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cer- vix, and endometrium. Int J Gynaecol Obstet,2009,105 (2) : 103- 104.

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