痰热清注射液防治急性放射性肺炎的临床研究

Clinical study of prophylactic effect with Tanreqing injection on acute radiation pneumonitis

目的探讨痰热清注射液对急性放射性肺炎的防治作用。方法将诊断明确的首次接受放射治疗的68例肺癌患者随机分为治疗组35例和对照组33例，治疗组在放射治疗的同时应用痰热清注射液；对照组仅行单纯的放射治疗。通过观察两组急性放射性肺炎的发生率及发生时间，评价痰热清注射液对放射性肺炎的防治作用。结果治疗组与对照组放射性肺炎的发生率分别为11．4％和33．3％，治疗组明显降低，差异有统计学意义（P〈0．05）；治疗组放射性肺炎发生时间相对延迟（P〈0．05）。结论痰热清注射液能降低急性放射性肺炎的发生率，延迟发生时间。

Objective To investigate the effect of Tanreqing injection on radiation pneumonitis. Methods Sixty-eight cases with lung cancer were randomly divided into treatment group （n = 35 ） and control group （n = 33）. In the treatment group, the patients were treated by radiation therapy and Tanreqing injection. In the control group, the patients were treated by radiation therapy only. The effect of Tanreqing injection on radiation pneumonitis were evaluated by observing the incidence of radiation pneumonitis and the occuring time. Results The incidence of radiation pneumonitis were 11.4% in the treatment group, while were 33.3% in the control group, there was significant differnce between the two groups （ P 〈 0. 05 ）. The radiation pneumonitis occuring time of the treatment group was later than that of the control group （P 〈 0. 05 ）. Conclusions Tanreqing injection can reduce the incidence of radiation pneumonitis and delay the occuring time.