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盐酸厄洛替尼合成路线图解 被引量:5

Graphical Synthetic Routes of Erlotinib Hydrochloride
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摘要 盐酸厄洛替尼(erlotinib hydrochloride,1),化学名为N-(3-乙炔基苯基)-6,7-二(2-甲氧基乙氧基)-4-喹唑啉胺盐酸盐,是美国OSI Pharmaceuticals公司开发的4-氨基苯基喹唑啉类口服抗肿瘤药,2004年美国FDA批准上市,临床用于治疗胰腺癌和转移性非小细胞肺癌。
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2012年第2期153-156,共4页 Chinese Journal of Pharmaceuticals
基金 国家“重大新药创制”科研重大专项(2009ZX09301-007)
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参考文献23

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二级参考文献29

  • 1王肇炎,王尔兵.分子靶抗癌药:伊丽沙治疗非小细胞肺癌的临床效益[J].癌症进展,2004,2(6):458-461. 被引量:1
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共引文献11

同被引文献38

  • 1牛明浩,益兵,张久惠,王哲烽.来那替尼(neratinib)合成路线图解[J].中国药物化学杂志,2020,30(5):318-320. 被引量:1
  • 2刘敏,胡昌勤.力达霉素标准品量值传递方法的研究[J].药物分析杂志,2004,24(4):380-384. 被引量:14
  • 3王成峰,林原斌.Vilsmeier法合成3,4-二甲氧基苯甲醛的研究[J].长沙电力学院学报(自然科学版),2004,19(4):87-88. 被引量:10
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