基于文本挖掘技术分析西药和中成药治疗再生障碍性贫血的规律

Rules of treating aplastic anemia with Western medicines and Chinese patent medicines based on text mining technique

目的利用文本挖掘技术探索西药、中成药治疗再生障碍性贫血的规律。方法在中国生物医学文献数据库中收集治疗再生障碍性贫血的相关文献,建立Access数据库,运用SQL数据平台处理数据,并结合人工降噪,分析西药、中成药的用药规律。结果司坦唑醇、环孢素A、抗胸腺细胞球蛋白、环磷酰胺、抗淋巴细胞球蛋白等为文献中出现的高频西药,复方皂矾丸、再障生血片等为文献中出现的高频中成药。结论利用文本挖掘的方法,从文献报告频数方面呈现了西药、中成药治疗再生障碍性贫血的用药规律,尤其是西药、中成药联合应用还值得进一步研究。

Objective To explore the rules of treating aplastic anemia with Western medicines and Chinese patent medicines by applying text mining technique. Methods The relevant literature about treating aplastic anemia were collected from Chinese Medical Current Contents （CMCC） and a Access database was established. The data were treated with SQL platform and the administration rules of Western medicines and Chinese patent medicines were analyzed combining artificial noise reduction. Results Stanozolol, cyclosporin A, antithymocyte globulin （ATG）, cyclophosphamide and antilymphocyte globulin （ALG） were Western medications with high-frequency in the literature, and Fufang Zaofan Wan and Zaizhang Shengxue Pian were Chinese patent medicines with high-frequency. Conclusion The frequency in literature repots showed the administration rules of Western medicines and Chinese patent medicines in the treatment of aplastic anemia by applying text mining technique. The integrative administration of Western medicines and Chinese patent medicines is worth studying further.