摘要
睡眠剥夺(sleep deprivation,SD)对机体记忆的影响可通过多种机制实现。海马的突触可塑性是研究学习记忆机制的重要目标,长时程增强(long-term potentiation,LTP)和长时程抑制(long-term depression,LTD)是突触可塑性重要的功能指标,因而与SD造成的记忆损伤有关。
The influence of sleep deprivation(SD) on the memory function can be realized through a variety of mech-anisms.Hippocampal synaptic plasticity is the important target of the mechanisms of learning and memory,long-term potentia-tion(LTP)and long-term depression(LTD) are the important functional indicators of synaptic plasticity,thus,which is related with memory impairment caused by SD.
出处
《现代医药卫生》
2012年第1期85-86,共2页
Journal of Modern Medicine & Health
基金
江苏省大学生实践创新训练计划项目基金(994)
关键词
睡眠剥夺
记忆
长时程增强
长时程抑制
Sleep deprivation
Memory
Long-term potentiation(LTP)
Long-term depression(LTD)