以上消化道症状为主诉的抑郁症的中医疗效观察

Observation of Therapeutic Effects of Depression with Traditional Chinese Medicine: Upper Gastrointestinal Symptoms as the Main Complaint

目的研究以上消化道症状为主诉的抑郁症患者辨证口服中药的临床疗效;方法将符合诊断标准的以上消化道症状(如胃痛、胃胀、恶心等)为主诉的抑郁症患者80例,随机分为中药加帕罗西汀组和单纯帕罗西汀组治疗,观察治疗6个月前后汉密尔顿量表(HAMD)减分率及总有效率;结果中药加帕罗西汀组HAMD减分的幅度明显较帕罗西汀组为大(P<0.05),差异有统计学意义;结论根据中医辨证分型口服中药能提高患者依从性,且能更有效地改善以上消化道症状为主诉的抑郁症核心症状,值得临床推广应用。

Objective To study the clinical effects of orally taking Chinese drugs to treat depressed patients with upper gastrointestinal symptoms as main complaints.Methods Randomly divide 80 cases of depressed patients with upper gastrointestinal symptoms（for example,stomachache,gasteremphraxis,nausea and etc.）as main complaints consistently with the diagnosis standard into two groups： the paroxetine group combined with traditional Chinese medicine and pure paroxetine group.Observe the reductive ratio of Hamilton Depression Scale（HAMD） and the total effective rate before and after six months’ treatment.Results The deducted rate of the HAMD in the former group is obviously bigger（P〈0.05） than the latter one.The difference is statistically meaningful.ConclusionBased on TCM syndrome differentiation theory,oral administration of Chinese medicine can improve patients’ compliance and more effectively improve the core depressive symptoms with upper gastrointestinal symptoms as main complaints,which is worth being popularizing and applied into clinical practices.