VEGF和Dll4/Notch信号通路调控自然流产母胎界面血管发育的研究进展
摘要
健康的胎盘血管网络对胚胎的发育及胎盘正常的血液循环极其重要。许多研究证明在血管形成过程中,存在多个信号传导通路,VEGF和Dll4/Notch信号通路就是其中非常重要的两条通路。胎盘VEGF mRNA表达与该部位的血管形成有关,胎盘血管在妊娠期中不断形成,并与绒毛一起植入子宫蜕膜层,
出处
《中医药临床杂志》
2012年第1期83-85,共3页
Clinical Journal of Traditional Chinese Medicine
参考文献20
-
1Yan M,Plowman GD. Delta-like 4/Notch signaling and its therapeutic implications. Clin Cancer Res,2007,13 ( 24 ) : 7243 -7246.
-
2Sugino N, Kashida S, Karube-Harada A, et al. Expression of vascular endothelial growth factor(VEGF) and its receptors in human endome- trlum throughout the menstrual cycle and in early pregnancy. Repro- duction,2002,123 (3) :379 -387.
-
3Ehebauer M, Hayward P, Aiias AM. Notch, a universal arbiter of cell fate decisions. Science, 2006,314 : 1414.
-
4Rehman AO, WangCun-Yu. Notch signaling in the regnla-tion of tumor angiogenesis, TrendsCellBio, 1 2006,16:6- 9.
-
5Siekmann AF, Lawson ND. Notch signaling limits angiogenic cell be- haviour in developing zebrafish arteries. Nature,2007,445:781 - 784.
-
6Williams CK, Li JL, Murga M, et al. Up-regulation of the Notch ligand Delta-like4 inhibits VEGF-induced endothelial cell function. Blood, 2006,107:931- 939.
-
7Dai J, Rabie AB. VEGF:an essentialmediator of both angiogenesis and endochondral ossification. JDentRes,2007,86 ( 10 ) : 937-950.
-
8Beck L, D" amore PA. Vasculr development:cellular and molecular regulation. FASEB J,2008,11:356-373.
-
9Dlrit Shweiki, Ahuva Ltin, Gera Neufeld, et al. Patterns of expression of vascular endothelial growth factor and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. Clin Invest, 1993,91: 2235-2243.
-
10Jain RK. Moleeular regulation of vessel maturation. Nat Med, 2003, 9:685 - 690.
-
1岳呈娟.减少婴幼儿20%甘露醇输液外渗的方法[J].济宁医学院学报,2011,34(1):53-53. 被引量:1
-
2毛秋云,田芳,任秀贞.小儿颅内肿瘤的围手术期护理[J].山东医药,2003,43(5):30-31.
-
3邹宇辉,岳志健.血管生成中DLL4/Notch信号通路的作用及其与VEGF、NO的关系[J].广东医学,2011,32(8):1082-1084. 被引量:3
-
4朱园园,毕明宏.DLL4/NOTCH通路与肿瘤血管生成关系研究进展[J].临床肺科杂志,2012,17(1):125-126. 被引量:2
-
5梁娜(综述),田伟(审校).MRI在胎盘植入中的研究进展[J].实用放射学杂志,2013,29(2):315-318. 被引量:30
-
6刘航,汪伟民,张剑波,顾海涛,王继见,周世骥.HIF-2α-VEGF-Notch信号通路在高强度聚焦超声不完全消融后肝癌中的作用[J].第三军医大学学报,2017,39(7):608-615. 被引量:6
-
7杨金锋,宋莉莉.超声诊断胎盘血管及胎膜破裂1例[J].中国医学影像学杂志,2015,23(8):626-626. 被引量:1
-
8孕妇注射类固醇不宜贪多[J].齐鲁护理杂志,2009,15(2S):78-78.
-
9李顺燕.176例药物流产患者的护理体会[J].中国医药指南,2010,8(21):144-145.
-
10吴丹.11例胎盘植入米非司酮与甲氨蝶呤治疗的护理[J].天津护理,2007,15(2):76-76.