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A novel approach towards dethioacetalization reactions with H_2O_2-SOC1_2 system

A novel approach towards dethioacetalization reactions with H_2O_2-SOC1_2 system
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摘要 A simple and efficient protocol for the deprotection of dithioacetal,1,3-dithianes and 1,3-dithiolanes has been developed using H_2O_2-SOC1_2 reagent system.In addition to the absence of overoxidation products for oxidation-prone substrates,high chemoselectivity, the low cost and availability of the reagents,simplicity of the method,short reaction times,and excellent yields can also be considered as strong points for this method. A simple and efficient protocol for the deprotection of dithioacetal,1,3-dithianes and 1,3-dithiolanes has been developed using H_2O_2-SOC1_2 reagent system.In addition to the absence of overoxidation products for oxidation-prone substrates,high chemoselectivity, the low cost and availability of the reagents,simplicity of the method,short reaction times,and excellent yields can also be considered as strong points for this method.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第1期81-85,共5页 中国化学快报(英文版)
基金 the Razi University Research Council for partial support of this work
关键词 Deprotection Carbonyl protecting group Dethioacetalization Dithioacetals Hydrogen peroxide Deprotection Carbonyl protecting group Dethioacetalization Dithioacetals Hydrogen peroxide
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