氟罗沙星葡萄糖注射液治疗细菌感染性疾病150例

THE EFFICACY AND SAFETY OF FLEROXACIN GLUCOSE INJECTION IN TREATMENT OF BACTERIAL INFECTIONS

目的 :验证氟罗沙星葡萄糖注射液对细菌性感染性疾病的疗效及其安全性。方法 :采用随机对照开放试验方法 ,选用氧氟沙星葡萄糖注射液作对照药。结果 :氟罗沙星葡萄糖注射液与氧氟沙星葡萄糖注射液的有效率分别为 87.9%与 74 % ,差异显著 (P <0 .0 1) ;两组患者细菌清除率为 88.8%和 85 .7% (P >0 .0 5 ) ;两组患者不良反应发生率分别为 15 .0 %和 16.0 % ,无显著差异 (P >0 .0 5 )。结论 :氟罗沙星葡萄糖注射液是一种广谱、有效、安全的抗菌药物。

OBJECTIVE:To verify the efficacy and safety of fleroxacin glucose injection METHODS:A randomized,controlled open method was adopted in the study using ofloxacin glucose injection as reference.RESULTS:The effective rate;bacterial clearance rate;and incidence of side effect in the active and control group were 87.9%and 74%;88.8%and 85.7%;and 15.0% and 16.0%respectively.CONCLUSION:Fleroxacin glucose injection is an effective and safe antibiotic with broad antibacterial spectrum.