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超声检测大脑中动脉峰值流速对预测胎儿重型地中海贫血的价值

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摘要 目的:探讨超声检测胎儿大脑中动脉血流峰值流速(MCA-PSV)对产前预测重型地中海贫血的价值。方法:超声检测350例不同孕龄胎儿MCA-PSV,显著升高(高于同孕龄胎儿中位数的1.5倍)者转送广东省妇幼保健院做产前诊断,并在本院对该孕妇进行每隔2周超声复查胎儿情况,连续监测至少3次,并记录胎儿出现腹水的时间及产前诊断的结果。结果:15例胎儿MCA-PSV显著升高,其中重型地中海贫血胎儿13例,假阳性2例。重度贫血胎儿MCA-PSV较同孕龄正常对照组胎儿MCA-PSV明显增高,两组差异有统计学意义(P<0.05),以MCA-PSV高于同孕龄胎儿中位数的1.5倍为标准,超声预测重度胎儿贫血的敏感性100%,假阳性13.3%。结论:超声检测MCA-PSV是产前预测胎儿重型地中海贫血的有效方法。
出处 《中国社区医师(医学专业)》 2012年第3期230-231,共2页
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