3,4-二硝基吡唑的合成

Synthesis of 3,4-Dinitropyrazole

吡唑经硝化、重排、硝化三步反应合成了潜在的TNT替代物——3,4-二硝基吡唑,其结构经1H NMR和IR确证。并对第三步硝化反应条件进行了优化,单步收率41%。

A candidate for TNT,3,4-dinitropyrazole,was synthesized from pyrazole by a three-step reaction of nitration,rearrangement and nitration.The reaction condition of the 3rd step was optimized in yield of 41%.The structure was confirmed by 1H NMR and IR.