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VEGF与MUC1基因在甲状腺癌中的表达及意义 被引量:1

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摘要 目的:探讨转移血管内皮生长因子与多态性上皮黏蛋白1(MUC1)基因在甲状腺中的表达及临床意义。方法:采用定量RT2PCR与图像扫描定量分析技术和免疫组化方法(SABC法)检测,分别检测64例甲状腺癌中MUC1基因和VEGF的表达水平。结果:MUC1基因在甲状腺癌中表达率73.43%(47/64);MUC1在无淋巴结转移组中的检出率69.44%(25/36);在淋巴结转移组中的检出率78.57%(22/28),P>0.05),VEGF在甲状腺癌中表达率78.12%(50/64)。结论:检测MUC1基因与VEGF的表达水平可能有助于判断甲状腺癌是否转移;血管内皮生长因子与MUC1的高表达可能在甲状腺癌转移过程中具有内在联系。
作者 崔颖 牧仁
出处 《中国社区医师(医学专业)》 2012年第2期259-259,共1页
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参考文献1

  • 1Klein M, Picard E, Vignand JM. Vascular endothelialgrow th factor(VEGF) gene and protein:stro ng ex pr ession in thyro iditis and thy roid carcinoma. J Endocr inol, 1999,161:41 - 49.

同被引文献17

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