单乙基甘氨酰二甲苯胺试验预测重症监护病人发生多器官功能衰竭及预后

MEGX test in predicting the risk of developing MOF and prognosis in ICU patients

目的 比较单乙基甘氨酰二甲苯胺（ＭＥＧＸ）肝功能试验和其余肝功能试验在预测外科重危监护（ＩＣＵ）病人发生多器官功能衰竭（ＭＯＦ）及预后方面的作用。方法 １７ 例ＩＣＵ重危监护病人均于术后转入ＩＣＵ病房，术后经３ ｄ 行ＭＥＧＸ肝功能试验及其它肝功能试验。结果 比较ＭＯＦ组和未发生ＭＯＦ组ＭＥＧＸ值有显著差异（Ｐ＜ ０．０５），其余肝功能试验比较未见明显差异（Ｐ＞ ０．０５）。结论 ＭＥＧＸ试验是检测肝功能和预测ＩＣＵ重危病人发生ＭＯＦ及预后的敏感试验。

Objective To compare the sensitivity of the MEGX liver function test and conventional liver function test in predicting the risk of developing MOF and prognosis in ICU patients.Methods The study includes 17 patients transfered from the operating room to the intensive care unit,the MEGX test and other liver function tests were performed 3 days after operation.Results The MEGX parameter difference between the MOF group and non MOF group was significant(P<0.05),there was no difference comparing conventional liver function parameter between the two groups(P>0.05).Conclusion MEGX test is a sensitive test in predicting the risk of developing MOF and prognosis in ICU patients. [