多普勒测量门静脉最大血流速度鉴别诊断无症状性脾肿大

Potential of Doppler Measurement of Maximum-portal Folw Velocity in the Differential Diagnosis of Asymptomatic Splenomegaly

目的：探讨脉冲多普勒测量门静脉最大血流速度鉴别诊断无症状性脾肿大的意义。材料和方法：早期肝硬化性脾肿大１０例，血液病性脾肿大１０例，正常健康对照１０例，分别采用脉冲多普勒测量三组门静脉最大血流速度。结果：血液病组门静脉最大血流速度（２６．４± ２．４ｃｍ／ｓ）明显高于早期肝硬化组（１４．８±２．１ｃｍ／ｓ，Ｐ＜０．００１），血液病组门静脉最大血流速度比正常对照组明显偏高。结论：多普勒测量门静脉最大血流速度可为鉴别诊断无症状性脾肿大提供一项可靠预测指标。

Purpose: In order to evaluate clinical value of maximum-protal flow velocity (MPFV) in the diagnosis of asymptomatic splenomegaly, 20 patients with splenomegaly were exami ned with color ampler sonography. Material and Methods: MPFV was measured in 10 patients of early-stage liver cirrhosis (group 1 ) and 10 of myelolymp hoproliferative disorders (group 2 ). The control group consist s of 10 normal volunteers. Results: MPFV of group 2 was significantly higher than that of group 1 (26. 4 i 2. 4cm/s vs 14. 8 t 2. Icm/s, p< 0. 001 ). COmpared with the control group, group 2 exhibited much higher MPFV (P< 0* 001 ), but the value in group I was lower (P< 0. 05). With regard to the diameter of POrtal vein, no significant difference was, found between the two groups. Conclusions: MPFV is proven a reliable parameter for the differential diagnosis of asyrnptomatic splenomegaly. The higher MPFV value suggests myelol ymphoproliferative disorders, the lower one invariably indicates early-stage liver cirrhosis.