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Th17细胞与呼吸道变应性疾病的研究进展 被引量：2

Progress in the study of Thl7 cell and allergic airway disease
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摘要 Th17细胞是新近认定的不同于Th1和Th2的特有T细胞系,与其他免疫细胞协调介导各种免疫反应,在一些原来认为由Th1、Th2介导的变应性疾病中起重要作用。本文对Th17细胞及其产生的细胞因子:IL-17、IL-6、INF-α及相关细胞因子IL-23在变应性疾病中的作用及研究进展进行综述。 Thl7 cells were identified as a distinct T-cell lineage different from Thl and Th2 recently,with the function of cooperatively mediate various inununologic responses and playing important roles in allergic diseases with other immune cells which were considered to be mediated by Th1 and Th2 originally.This review will summarize the roles and the progress in research of Thl7 cells and its cytokines：IL-17 IL-6、INF-α and related to it：IL-23 in allergic disease.
作者 熊瑛 章诗富
机构地区 广东医学院附属医院耳鼻咽喉头颈外科
出处 《海南医学》 CAS 2012年第2期125-127,共3页 Hainan Medical Journal
关键词 THL7细胞 变应性疾病 IL-17 IL-6 INF-Α IL-23 Thl7 cell Allergic disease IL-l7 INF-α IL-6 IL-23
分类号 R562 [医药卫生—呼吸系统]
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  • 1谈永基 陈灏珠 等.偏头痛.实用内科学（第10版）[M].北京:人民卫生出版社,1997.2242-2243.
  • 2Hoshino A, Tanaka Y, Akiba H, et al. Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma. Eur J Immunol 2003; 33(4):861-9.
  • 3Yssel H, Groux H. Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases. Int Arch Allergy Immunol 2000;121(1):10-8.
  • 4Swanson MA, Lee WT, Sanders VM. IFN-gamma production by Th1 cells generated from naive CD4 + T cells exposed to norepinephrine. J Immunol 2001; 166(1):232-40.
  • 5Huang HC, Huang YL, Chang JH, et al. Possible mechanism of immunosuppressive effect of scoparone(6, 7-dimethoxycoumarin). Eur J Pharmacol 1992; 217(2-3):143-8.
  • 6Fang Y, Li Z, Watanabe Y. Pharmacokinetics of a novel anti-asthmatic, scoparone, in the rabbit serum assessed by a simple HPLC method. J Ethnopharmacol 2003; 86 (1):127-30.
  • 7ZhaoYF LiZ LiSC etal.Extraction of scoparone from Artenisia Scoparia of Shengyang[J].中国医科大学学报,1997,26(6):575-6.
  • 8Duan W, Kuo IC, Selvarajan S, et al. Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma. Am J Respir Crit Care Med 2003; 167(2):185-92.
  • 9Boulares AH, Zoltoski A J, Sherif ZA, et al. Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma. Am J Respir Cell Mol Biol 2003; 28 (3):322-9.
  • 10Xu SY, Bianm RL. Experimental methods of Pharmacology. Beijing:People Hygienic Publisher 1982:905-7.

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海南医学
2012年 第2期

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