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髓母细胞瘤相关miRNA的研究进展

The Research Progress on MicroRNA in Medulloblastoma
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摘要 髓母细胞瘤(medulloblastoma)是儿童颅内恶性程度极高的常见肿瘤之一,具体病因不明,预后极差。现阶段随着髓母细胞瘤分子遗传学研究的逐步深入,microRNA(miRNA)更成为研究的热点。本文将就miRNA与髓母细胞瘤的关系作一综述。 The cerebellar medulloblastoma is a highly malignant and invasive embryonal tumor in children. However, the cause of medulloblastoma is not clear and the prognosis is poor. The research on microRNA in medulloblastoma has become a hot topic. In this article, we reviewed the relations between medulloblastoma and microRNA.
作者 李立超 吕胜青 潘亚文
机构地区 兰州大学附属第二医院神经外科 第三军医大学附属新桥医院神经外科
出处 《中国神经肿瘤杂志》 2011年第4期279-283,共5页 Chinese Journal of Neuro-Oncology
基金 国家自然科学基金资助项目(No:30973075)
关键词 髓母细胞瘤 MIRNA 诊断与治疗 Medulloblastoma MicroRNA Diagnosis Therapy
分类号 R739.41 [医药卫生—肿瘤]
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参考文献32

  • 1Berezikov E,,Cuppen E,Plasterk RH,et al.Approaches to microRNA discovery. Nature Genetics . 2006
  • 2Makeyev EV,Maniatis T.Multilevel regulation of gene expression by microRNAs. Science . 2008
  • 3Liu X,Fortin K,Mourelatos Z,et al.MicroRNAs:biogenesis and molecular functions. Brain Pathology . 2008
  • 4Grunder E et al.MicroRNA-21suppression impedes medulloblastoma cell migration. European Journal of Cancer . 2011
  • 5de Antonellis P,Medaglia C,Cusanelli E,et al.MiR-34a Targeting of notch ligand delta-like1impairs CD15/CD133tumor-propagating cells and supports neural differentiation in medulloblastoma. PLoS One .
  • 6Godlewski J,Nowicki MO,Bronisz A,et al.Targeting of the Bmi-1oncogene/stem cell renewal factor by microRNA-128inhibits glioma proliferation and self-renewal. Cancer Research . 2008
  • 7Stenvang J,Silahtaroglu AN,Lindow M,et al.The utility of LNA in microRNA-based cancer diagnostics and therapeutics. Seminars in Cancer Bio . 2008
  • 8Lv SQ,Kim Y,Giulio F,et al.Genetic alterations in microRNAs in medulloblastomas. Brain Pathology .
  • 9SF Tavazoie,C Alarcon,T Oskarsson.Endogenous human microRNAs that suppress breast cancer metastasis. Nature . 2008
  • 10Zhang B,Pan X,Cobb GP,et al.MicroRNAs as oncogenes and tumor suppressors. Developmental Biology . 2007

二级参考文献51

  • 1Pillai RS. MicroRNA function: multiple mechanisms for a tiny RNA? RNA 2005; 11:1753-1761.
  • 2Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science 2005; 309:1519-1524.
  • 3Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116:281-297.
  • 4Fitzgerald K. RNAi versus small molecules: different mechanisms and specificities can lead to different outcomes. Curr Opin Drug Discov Dev 2005, 8:557-566.
  • 5Brennecke J, Stark A, Russell R.B, Cohen SM. Principles of microRNA-target recognition. PLoS Biol.2005; 3:e85.
  • 6Croce CM, Calin GA. miRNAs, cancer, and stem cell division. Cell 2005; 122:6-7.
  • 7Chen CZ, Li L, Lodish HF, Bartel DE MicroRNAs modulate hematopoietic lineage differentiation. Science 2004; 303:83- 86.
  • 8Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 2006; 94:776-780.
  • 9Hammond SM. MicroRNAs as oncogenes. Curr Opin Genet Dev 2006; 16:4-9.
  • 10Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006; 6:259-269.

共引文献207

中国神经肿瘤杂志
2011年 第4期

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