婴儿血管瘤的药物治疗

Drug Therapy for Infantile Hemangioma

婴儿血管瘤是儿童最常见的一种肿瘤,发病率达10%。婴儿血管瘤具有一定自限性,通常在1岁内出现快速增殖期,部分血管瘤可自行消退。有些婴儿血管瘤在快速增殖期出现溃疡、出血、畸形或者感染时,需要及时予以干预治疗。血管瘤的治疗方法多种多样,常用的药物治疗方法包括:糖皮质激素、干扰素、平阳霉素等。普萘洛尔是一种治疗婴儿血管瘤的新方法,安全有效。特别是对于伴有一些严重并发症,能够在合适的时机选择恰当的药物治疗非常重要。

Infantile Haemangiomas are the most common tumors of infancy affecting approximately 10% children.It is characterized by a rapid proliferating phase within one years old,some of them may spontaneously disappear.Sometimes intervention is required due to proliferative growth which is complicated by ulceration,bleeding,persistent aesthetic deformity or infection.Various drug therapeutic approaches to infant hemangiomas have been described.In recent years,a lot of methods have been proposed and applied,including corticosteroid,interferon α-2a,pingyangmycin and so on.Propranolol has recently been introduced as a novel modality for the treatment of proliferating haemangiomas and with fewer side effects.it is very important to give proper pharmacotherapy in right time.