淋巴细胞性甲状腺炎合并甲状腺乳头状癌临床病理分析

Clinicopathological analysis of lymphocytic thyroiditis and thyroid papillary carcinoma

目的:探讨淋巴细胞性甲状腺炎合并甲状腺乳头状癌的临床病理特征。方法:对我院及上海市第六人民医院2008-2010年手术切除的166例淋巴细胞性甲状腺炎、淋巴细胞性甲状腺炎合并甲状腺乳头状癌的病理资料进行回顾性分析。结果:淋巴细胞性甲状腺炎、淋巴细胞性甲状腺炎合并甲状腺乳头状癌的平均发病年龄分别为45.5岁、42.5岁,均女性多于男性。淋巴细胞性甲状腺炎合并甲状腺乳头状癌占淋巴细胞性甲状腺炎的25.9%,44例淋巴细胞性甲状腺炎合并甲状腺乳头状癌中35例为甲状腺乳头状微小癌,占淋巴细胞性甲状腺炎合并甲状腺乳头状癌的79.5%。淋巴细胞性甲状腺炎合并甲状腺乳头状癌中7例发生周围淋巴结转移(15.9%)。结论:淋巴细胞性甲状腺炎与甲状腺乳头状癌关系密切,淋巴细胞性甲状腺炎是具有恶性潜能的癌前期病变,淋巴细胞性甲状腺炎合并甲状腺癌以甲状腺乳头状癌多见,微小癌的比例高。

Objective：To study the Clinicopathological characteristics of lymphocytic thyroiditis（LT）with throid papillary carcinoma（TPC）.Methods： Total of 116 cases of LT and LT with TPC from 2008-2010 were reviewed.Results： The mean age of onset was 45.5 and 42.5,for LT and LT with TPC respectively.Female cases were more than male.35 cases of 44 LT with TPC were papillary microcarcinoma of thyroid（PMCT）（79.5%）.LT with TPC account for 25.9% in the LT,7 cases lymph-node metastases were found in the cases of LT with TPC（15.9%）.Conclusion： LT was closely related with TPC,It possesses the feature of a malignant potential of precancerous lesions.LT with TPC usually appears as papillary thyroid carcinoma,in which microcarcinoma takes a high proportion.