摘要
FES PET-CT显像在乳腺癌中的临床应用是通过FES与功能性雌激素受体(ER)特异结合特性,利用标准摄取值半定量地、客观地反映了患者活体内功能性ER的分布及其生物活性,判断乳腺肿瘤原发灶及转移灶、治疗前后肿瘤组织ER表达的异质性,对乳腺癌内分泌治疗提供依据。FES与FDG PET-CT对比显像提供的乳腺肿物定性、定量、定位及生物学行为的信息,能更好地对乳腺癌患者进行疗效评价和预后分析,给乳腺癌诊疗带来划时代的意义。
In the clinical application of breast cancer,FES PET-CT imaging,which is through its specific binding to functional estrogen receptors(ERs),semi-quantitatively and objectively reflects the distribution and biological activity of ERs by standard uptake value and detects the heterogeneity of ERs expression between primay lesions and metastases,lesions before treatments and ones after treaments in order to provide the basis of endocrine therapy of breast cancer.FES/FDG PET-CT compared imaging provides information about qualitation,quantitation,location and the biological behavior of breast tumor to evaluate the therapeutic efficacy and prognosis of breast cancer patients,and brings epoch-making significance to diagnosis and treatment of breast cancer.
出处
《现代肿瘤医学》
CAS
2012年第2期412-416,共5页
Journal of Modern Oncology