奥硝唑与定君生治疗细菌性阴道病84例疗效评价

An evaluation of 84 patients with bacterial vaginosis treated with ornidazole and Dingjunsheng

目的探讨评价奥硝唑与定君生治疗细菌性阴道病的临床疗效。方法回顾性分析我院2008年11月-2011年3月门诊处确诊为细菌性阴道炎并进行治疗的病例84例，将其随机分为2组，治疗组42例先口服奥硝唑6d，后应用定君生（乳酸杆菌活菌胶囊）10d，对照组为剩余42例病人，仅服用奥硝唑6d，评价其临床疗效。结果经过治疗后治疗组的总有效率为92．85％明显高于对照组的83．33％，差异具有统计学意义（P〈0．05），在随访中发现治疗组的复发率为0明显低于对照组11．9％，差异具有统计学意义（P〈0．05）。结论奥硝唑与定君生联合用药治疗细菌性阴道病疗效较单一用药好，值得在临床上推广。

Objective To explore the chnical efficacy of treating bacterial vaginosis with ornidazole and Dingjunsheng. Methods Retrospectively analyzed the 84 outpatients from our hospital from May, 2008 to March, 2011, who were diagnosed with bacterial vaginosis and treated at our hospital. Randomly divided them into two groups： treatment group with 42 cases, during the first 6 days, orally took ornidazole, then were treated with Dingjunsheng （lactic acid bacteria viable capsules） for 10 daya and control group with the remaining 42 patients, only took ornidazole for 6 days. Evaluate their clinical efficacies. Results After the treatment, the total effective rate of treatment group was 92.85%, which was significantly higher than that of control group（83.33%）; the differences was significantly obvious （P〈 0.05）. During the follow-up, treatment group＇ s rectmence rate was 0.0%, which was significantly lower than control group＇ s（11.9%）; the difference was significantly obvious （P〈 0.05）. Conclusion Using both ornidazole and Dingjunsheng to treat bacterial vaginosis is more effective than using only one of them, which is worth to be generalized in clinical practice.