151例糖耐量低减患者中医证候及聚类情况分析

TCM syndrome and clustering analysis research of 151 cases of IGT patients

目的:探讨糖耐量低减(IGT)人群中医证候及证型特点,为临床施治提供依据。方法:通过OGTT试验筛选IGT病例,记录包括腰臀比、体质量指数等一般项目;采用设计的中医证候问卷,专人采集四诊资料,累计积分,聚类分析,归纳证型。结果:151例IGT患者在纳入调查的症状中,出现频数居前10位的依次是:健忘(62.3%)、夜尿频多(55.6%)、自汗(53.0%)、神疲乏力(51.0%)、脘腹胀满(49.7%)、口干咽燥(45.7%)、痰多(42.4%)、口渴喜饮(41.1%)、眼睛干涩(37.7%)、大便干结(35.8%)。聚类分析结果151例IGT患者患者中,气阴两虚型78例(51.7%),脾虚痰湿型52例(34.4%),阳虚血瘀型21例(13.9%)。结论:IGT的发病多与脾虚、气虚、阴虚、血瘀等因素有关;IGT患者中,气阴两虚证多见。

Objective： To study characteristics of TCM syndrome and syndrome type in impaired glucose tolerance（IGT） population to provide basis for clinical treatment application.Methods： selected IGT cases by OGTT test,recorded the general items including waist-hip ratio,body mass index;a TCM questionnaire was adopted,collected information on four diagnostic,accumulated the points,conducted a cluster analysis to summarize syndrome.Results： among the 151 cases of IGT patients involved in the symptom survey,the top 10 occurrence frequency sequence were as follows： forgetfulness（62.3%）,nocturia（55.6%）,spontaneous perspiration（53.0%）,spiritlessness and fatigue（51.0%）,abdominal distention（49.7%）,dry mouth and throat（45.7%）,excessive phlegm（42.4%）,thirst with liking for fluids（41.1%）,dry eyes（37.7%）,dry bound stool（35.8%）.Cluster analysis shows that among the 151 cases of patients with IGT,78 cases（51.7%） are type of deficiency of both Qi and Yin,52 cases（34.4%） are type of spleen-asthenia and phlegm-damp,21 cases（13.9%） are type of Yang deficiency and blood stasis.Conclusion： IGT incidence is relevant with some factors such as spleen asthenia,Qi deficiency,Yin deficiency,and blood stasis;deficiency of both Qi and Yin are very common in IGT patients.