复方甲氧那明治疗感染后咳嗽的临床疗效

Clinical efficacy of compound methoxyphenamine for cough following acute upper respiratory tract infection

目的观察复方甲氧那明治疗感染后咳嗽的临床疗效。方法将182例感染后咳嗽患者按病历单双号随机分为治疗组(n=91)和对照组(n=91)。治疗组口服复方甲氧那明胶囊2粒/次,3次/d,7 d一疗程;对照组口服阿奇霉素片0.5 g/次,1次/d,3 d一疗程;复方甘草片4片/次,3次/d,7 d一疗程。分别观察其疗效和不良反应。结果治疗后两组咳嗽评分均下降,且治疗组低于对照组(P<0.05)。治疗组和对照组的有效率分别为92.31%和62.64%,两组疗效有显著性差异(P<0.05)。两组均未发生严重不良反应。结论复方甲氧那明治疗感染后咳嗽不但安全、有效,而且可以避免滥用抗生素而造成的细菌耐药。

Objective To investigate the clinical efficacy of compound methoxyphenamine for cough following acute upper respiratory tract infection.Methods A total of 182 patients with cough following acute upper respiratory tract infection were randomly divided into treatment group（n=91） and control group（n=91） according to odd-even number of cases.The patients received oral administration of compound methoxyphenamine 2 capsules three times daily for 7 d in treatment group,and oral administration of azithromycin 0.5 g three times daily for 3 d and compound liquorice tablets 4 tablets three times daily for 7 d in control group The therapeutic effects and the adverse reactions in two groups were observed.Results After treatment,the scores of cough in both treatment group and control group decreased,and the score in treatment group was significantly lower than that in control group（P0.05）.The effective rates in treatment group and control group were 92.31% and 62.64%,respectively（P0.05）.No serious adverse drug reactions occurred in both groups.Conclusion The compound methoxyphenamine for cough following acute upper respiratory tract infection not only is safe and effective,but also could avoid the bacterial resistance resulted from abusing antibiotics.