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Stathmin、PDCD4、Caveolin-1蛋白在消化系统肿瘤中的研究进展

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摘要 我国已登记恶性肿瘤发病率为276.16/10万,每年新发病例300万,其中消化系统肿瘤占60%~70%,且呈年轻化趋势。恶性肿瘤的发生是由于先天遗传缺陷或后天环境因素影响导致原癌基因激活/过量表达、抑癌基因失活或调节失控共同参与的复杂过程。Stathmin、PDCD4、Caveolin-1分别为原癌基因、抑癌基因和双重调控基因的表达产物,在肿瘤的发生、发展中具有重要作用,其功能缺陷是肿瘤发病的重要机制之一。
机构地区 河北医科大学
出处 《实用癌症杂志》 2012年第1期86-88,共3页 The Practical Journal of Cancer
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参考文献30

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二级参考文献114

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