超声功能性成像评估肝脏纤维化程度的研究现状

Research Status of Ultrasound Functional Imaging in Assessment of Hepatic Fibrosis

超声功能性成像目前包括两大领域:超声对比造影的研究和超声弹性成像的研究,实时灰阶超声造影测定肝动静脉渡越时间及肝实质时间-强度曲线可反映肝硬化引起的肝脏血流灌注和血流动力学的异常改变,从而间接对肝纤维化程度进行评估;而基于超声生物静态结构力学的声力式触诊组织弹性量化技术则可直接反映肝脏弥漫性病变组织的硬度,这是一种实时、无创、简单易行,并可在活体上进行可重复操作的肝脏纤维化程度的定量分析方法。

At present,ultrasound functional imaging contains two fields：ultrasound elastography and contrast-enhance ultrasound.Using real time contrast-enhance ultrasound in determination of hepatic artery vein transit time and liver parenchyma time intensity curve can reflect the anomaly change of liver blood perfusion and hemodynamics caused by hepatocirrhosis,thus evaluate the degree of hepatic fibrosis indirectly;but virtual touch tissue quantification can reflect the hardness of diffuse liver diseases tissue.It′s a quantitative analysis method with features of real time,noninvasive,simple and easy,conducting in living body which canbe operated repeatedly.