血清C反应蛋白和白细胞计数联合检测在小儿肺炎中的应用

Application of Serum C-reactive Protein Combined with White Blood Cells Count in Diagnosis of Pneumonia in Children

目的探讨血清C反应蛋白(CRP)和白细胞计数(WBC)联合检测在小儿肺炎诊断中的应用价值。方法 116例小儿肺炎根据诊断结果分为细菌感染组(62例)和病毒感染组(54例),同期选择健康体检儿童(80例)作为健康对照组,检测各组患者血清CRP、WBC,并进行比较。结果细菌感染组CRP、WBC高于病毒感染组和健康对照组,差异有统计学意义(P<0.01);病毒感染组CRP、WBC与健康对照组比较差异无统计学意义(P>0.05)。细菌感染组CRP、WBC、CRP+WBC三项检测的阳性检出率明显高于病毒感染组(P<0.01)。结论血清CRP、WBC联合检测对肺炎病原体的鉴别和诊断有较高的特异性,提高了细菌性肺炎诊断的准确性和早期检出率。

Objective To investigate the value of serum C-reactive protein（CRP）combined with white blood cell count（WBC）in the diagnosis of pneumonia in children.Methods 116 cases of children with pneumonia were divided into two groups according to the diagnosis results：bacterial infection group（62 cases）,viral infection group（54 cases）.Over the same period 80 healthy children were selected as the healthy control group,levels of serum CRP,WBC of each group were tested and compared.Results Levels of serum CRP,WBC in bacterial infection group were significantly higher than that of the virus infection and the healthy control group（P0.01）.Compared with healthy control group,the levels of serum CRP,WBC in virus infection group had no significant difference（P0.05）.The levels of serum CRP,WBC and CRP＋WBC three detection positive rate were significantly higher than that of the virus infection（P0.01）.Conclusion The combined detection of serum CRP,WBC has a higher specificity to pathogen identification and diagnosis of pneumonia,which improves diagnostic accuracy of bacterial pneumonia and early detection rate.