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孟鲁司特钠治疗儿童哮喘的临床观察 被引量:4

Clinical Observation of Montelukast Sodium in the Treatment of Childhood Asthma
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摘要 目的观察孟鲁司特钠片联合吸入型糖皮质激素治疗儿童哮喘的疗效。方法将78例哮喘患儿分为治疗组及对照组,治疗组在对照组的基础上加用孟鲁司特钠片口服,观察临床症状控制时间及复发率。结果治疗组临床症状控制时间为(5.41±0.95)d,与对照组(7.35±0.75)d相比,差异有统计学意义(P<0.05)。同时其复发率明显低于对照组。结论孟鲁司特钠片联合吸入激素治疗儿童哮喘可明显提高治疗效果及降低哮喘复发率。 Objective To observe the effect of montelukast sodium tablets combined corticosteroid inhalation in the treatment of childhood asthma.Methods 78 patients with asthma were randomly divided into the treatment group and the control group,the treatment group were treated by montelukast sodium tablets on the basis of treatment in the control group,observe control time of clinical symptom and recurrence rate.Results Control time of clinical symptom of the treatment group was(5.41±0.95)days,and the control group was(7.35±0.75)days,the difference was statietically significant(P0.05).At the same time,the recurrence rate was significantly lower than that of the control group.Conclusion The treatment of montelukast sodium tablets combined with inhaled corticosteroids for childhood asthma can significantly impove the treatment effect and reduce the recurrence rate of asthma.
出处 《医学综述》 2012年第2期320-320,F0003,共2页 Medical Recapitulate
关键词 儿童哮喘 孟鲁司特钠 吸入型糖皮质激素 Children asthmatic Montelukast Inhaled corticosteroids
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  • 1瞿申红,李添应,陈彦球,林志斌,欧志英.白三烯受体拮抗剂和吸入性皮质激素在变应性鼻炎中的应用[J].临床耳鼻咽喉科杂志,2005,19(12):557-559. 被引量:14
  • 2彭秋莹,陈爱欢.白三烯研究进展及其在婴幼儿喘息性疾病中的作用[J].中华儿科杂志,2006,44(7):553-556. 被引量:94
  • 3隗远祥,王宏伟,康闽.白三烯受体途径在川崎病血管免疫损伤中的作用[J].实用儿科临床杂志,2007,22(9):663-664. 被引量:4
  • 4Peters-Golden M, Gleason MM, Togias A. Cysteinyl leukotrienes: muhi-functional mediators in allergic rhinitis [J]. Clin Exp Allergy, 2006,36 (6) : 689-703.
  • 5Scow DT, Luttermoser GK, Dickerson KS. Leukotriene inhibitors in the treatment of allergy and asthma [J]. Am Fam Physician, 2007,75 ( 1 ) : 65-70.
  • 6Figueroa DJ, Borish L, Baramki D, et al. Expression of cysteinyl leukotriene synthetic and signalling proteins in inflammatory cells in active seasonal allergic rhinitis [J]. Clin Exp Allergy. 2003,33(10) : 1380-1388.
  • 7Ho CY, Tan CT. Comparison of antileukotrienes and antihis-tamines in the treatment of allergic rhinitis [J]. Am J Rhinol, 2007,21 ( 4 ) : 439-443.
  • 8Philip G, Malmstrom K, Hampel FC, et ol. Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring [J]. Clin Exp Allergy, 2002,32 ( 7 ) : 1020-1028.
  • 9Philip G, Williams-Herman D, Patel P, et al. Efficacy of mon-telukast for treating perennial allergic rhinitis [J]. Allergy Asthma Proc, 2007,28(3) :296-304.
  • 10Scadding GK, Durham SR, Mirakian R, et ol. BSACI guidelines for the management of allergic and non-allergic rhinitis [J]. Clin Exp Allergy ,2008,38( 1 ) : 19-42.

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