超声监测并卡前列甲酯在高危人工流产术中的应用

Application of ultrasound guidance combined with Carboprostmethyl for the high risk artificial abortion

目的:评价应用超声监测并卡前列甲酯在高危人工流产手术中手术时间,出血量及人工流产并发症子宫穿孔,月经量减少等方面是否低于传统高危人工流产手术。方法:回顾性分析早孕合并有高危因素的患者15 399例,术前30 min均肛塞卡孕栓0.5 mg。在超声引导下手术12 398例(观察组),传统人工流产术3 001例(对照组),观察上述两组患者在手术时间,术中出血量,人工流产并发症:人流不全、漏吸、子宫穿孔、月经量减少、宫颈粘连等指标上的差异。结果:观察组手术时间(4.1±0.5)min和术中出血量(15.2±5.3)ml,均低于对照组手术时间(6.8±1.0)min和术中出血量(20.4±6.8)ml,两组相比差异具有统计学意义。观察组并发症发生率1.13‰,明显低于对照组5.66‰,差异具有统计学意义(P<0.001)。结论:超声引导并卡前列甲酯可以降低人工流产手术的手术时间及术中出血量,减少高危人工流产手术并发症的发生,如不全流产、漏吸、子宫穿孔、宫腔粘连、宫颈粘连等。超声引导并卡前列甲酯在高危人工流产术中的应用值得推广。

Objective：To evaluate whether application of ultrasound guidance combined with Carboprostmethyl in the high risk artificial abortion would significantly superior to traditional artificial abortion in preventing complication.Methods：The clinical data of 15 399 patients with the high risk pregnancy were analyzed.For the all the patients,Carboprostmethyl was used before abortion.Incidence of complication in 12 398 women（observation group）with the high risk pregnancy for ultrasound guidance artificial abortion were observed and compared with that of 3 001 women（control group） with the high risk pregnancy for traditional artificial abortion.Results：The time of artificial abortion（4.1±0.5min） and the hemorrhage of abortion（15.2±5.3ml） in observation group were all lower than the control group（6.8±1.0min） and（20.4±6.8）,the different were significant.The incidence of complication in observation group（1.13‰） was significantly lower than the control group（5.66‰）.Conclusion：Ultrasound guidance combined with Carboprostmethyl in high risk artificial abortion can effectively low the time and hemorrhage of abortion and prevent the complications.