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氟西汀合并甲状腺素片治疗难治性抑郁症疗效观察

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摘要 目的:研究氟西汀合并甲状腺素片治疗难治性抑郁症患者的临床疗效。方法:将72例难治性抑郁症患者随机分两组,氟西汀合并甲状腺素片组(治疗组),单用氟西汀组(对照组),治疗8周,于入组前,治疗2、4、8周未分别应用汉密顿抑郁置表(HAMD17项)进行疗效评定,并用治疗中出现的症状量表(TESS)评定不良反应。结果:治疗组第4周起HAMD评分显著下降(P<0.01),并明显低于对照组(P<0.01),两组不良反应无明显差异(P>0.05)。结论:氟西汀合并甲状腺素片对难治性抑郁症疗效确切。
出处 《中国社区医师(医学专业)》 2012年第4期181-181,共1页
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  • 1Quitkin FM, Rabkin JG, Ross D, et al. Duration of antidepressant drug treatment. What is an adequate trial? Arch Gen Psychiatry, 1984, 41:238-245.
  • 2Quitkin FM, Rabkin JG, Ross D, et al. Identification of true drug response to antidepressants. Use of pattern analysis. Arch Gen Psychiatry, 1984, 41:782-786.
  • 3Stewart JW, Quitkin FM, McGrath PJ, et al. Use of pattern analysis to predict differential relapse of remitted patients with major depression during 1 year of treatment with fluoxetine or placebo. Arch Gen Psychiatry, 1998,55:334-343.
  • 4Posternak MA, Zimmerman M. Is there a delay in the antidepressant effect? A meta-analysis. J Clin Psychiatry, 2005, 66 : 148-158.
  • 5Papakostas GI, Perlis RH, Scalia M J, et al. A meta-analysis of early sustained response rates between antidepressants and placebo for the treatment of major depressive disorder. J Clin Psychopharmacol, 2006, 26:56-60.
  • 6Taylor MJ, Freemantle N, Geddes JR, et al. Early onset of selective serotonin reuptake inhibitor antidepressant action : systematic review and meta-analysis. Arch Gen Psychiatry, 2006, 63:1217-1223.
  • 7Katz MM, Koslow SH, Frazer A. Onset of antidepressant activity- reexamining the structure of depression and muhiple actions of drugs. Depress Anxiety, 1996-1997, 4:257-267.
  • 8Katz MM, Bowden C, Stokes P, et al. Can the effects of antidepressants be observed in the first two weeks of treatment? Neuropsychopharmacology, 1997, 17 : 110-115.
  • 9Katz MM, Tekell JL, Bowden CL, et al. Onset and early behavioral effects of pharmacologically different antidepressants and placebo in depression. Neuropsychopharmacology, 2004, 29:566- 579.
  • 10Wade A, Friis Andersen H. The onset of effect for escitalopram and its relevance for the clinical management of depression. Curr Med Res Opin, 2006, 22:2101-2110.

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