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泊沙康唑治疗侵袭性真菌病研究进展

The research progress of Posaconazole in invasive fungal infection
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摘要 2006年美国食品药品管理局(FDA)批准上市的新型抗真菌药物——泊沙康唑(Posaconazole)。其化学结构与伊曲康唑同源,通过抑制麦角固醇的生物合成而发挥其抗真菌活性,具有抗菌谱广、生物利用度高、耐受性好等特征。
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2012年第2期154-157,共4页 Chinese Journal of Practical Internal Medicine
关键词 侵袭性真菌病 抗真菌药 泊沙康唑 invasive fungal infection antifungal agents Posaconazole
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参考文献21

  • 1Pfaller, Messer et al. In vitro activities of posaconazole ( Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans [ J ]. Antimicrob Agents Chemother,2001,45( 10) :2862 - 2864.
  • 2Pfaller MA, Messer SA, Boyken L, et al. In vitro activities of voricon- azole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program [ J ]. Diagn Microbial Infect Dis, 2004,48 ( 3 ) : 201 - 205.
  • 3Sabatelli F, Patel R, Mann PA, et al. In vitro activities of posacon- azole ,fluconazole, itraconazole, voriconazole, and arnphotericin B a- gainst a large collection of clinically important molds and yeasts [J]. Antimicrob Agents Chemother,2006,50(6) :2009 -2015.
  • 4Pfaller MA, Messer SA, Boyken L, et al. Global trends in the anti- fungal susceptibility of Cryptococcus neoformans ( 1990 to 2004 ) [ J]. J Clirt Microbiol,2005,43 ( 5 ) :2163 - 2167.
  • 5Espinel-Ingroff. In vitro antifungal activities of anidulafungin and micafungin,licensed agents and the investigational triazole posacon- azole as determined by NCCLS methods for 12,052 fungal isolates: review of the literature [ J ]. Rev Iberoam Micol,2003,20 (4) :121 - 136.
  • 6Sun QN, Fothergill AW, McCarthy DI, et al. In vitro activities of posaconazole,itraconazole, voriconazole, amphotericin B, and flucon- azole against 37 clinical isolates of zygomycetes [ J ]. Antimicrob A- gents Chemother,2002,46 (5) : 1581 - 1582.
  • 7Gilgado F, Serena C, Cano J, et al. Antifungal susceptibilities of the species of the Pseudallescheria boydii complex [ J ]. Antimicrob A- gents Chemother,2006,50 (12) :4211 - 4213.
  • 8Courtney R, Pai S, Laughlin M, et al. Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults [ J ]. Antimicrob Agents Chemother ,2003,47 (9) :2788 -2795.
  • 9Courtney R, Radwanski E, Lim J, et al. Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting heahhy men [ J ]. Antimicrob Agents Chemother, 2004,48 ( 3 ) : 804 - 808.
  • 10Vazquez GA, Skiest D J, Nieto L, et al. A multicenter randomized trial envaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects With HIV/AIDS [ J]. Clin hffect Dis,2006,42 ( 8 ) : 1179 - 1186.

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