3Travis JA,Hughes MG,Wong JM,et al.Hyaluronan enhances contraction of collagen by smooth muscle cells and adventitial fibroblasts:role of CD44 and implications for constrictive remodeling.Circ Res,2001,88(1):77-83.
5Nho RS,Xia H,Kahm J,et al.Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type Ⅰ collagen matrices through a betal integrin viability signaling pathway.J Biol Chem,2005,280(28):26630-26639.
6Hannigan GE,Leung-Hagesteijn C,Fitz-Gibbon L,et al.Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.Nature,1996,379(6560):91-96.
7Shafiei MS,Rockey DC.The role of integrin-linked kinase in liver wound healing.J Biol Chem,2006,281(34):24863-24872.
8Liu BC,Li MX,Zhang JD,et al.Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition.Am J Nephrol,2008,28(1):143-151.
3Arora PD,Narani N,McCulloch CA,et al.The compliance of collagen gels regulates transforming growth factor-beta induction of alpha-smooth muscle actin in fibroblasts.Am J Pathol,1999,154:871-872.
4Kagami-S,Kondo-S,Urushihara-M,et al.Overexpression of alphalbetal integrin directly affects rat mesangial cell behavior.Kidney Int,2000,58:1088-1097.
5Ruoslahti E,Integrins.J Clin Invest,1991,87:1-5.
6Hildebrand JD,Schaller MD,Parsons JT,et al.Identification of sequences required for the efficient localization of the focal adhesion kinase,pp125FAK,to cellular focal adhesions.J Cell Biol,1995,123:993-1005.
7Schlaepfer DD,Hanks SK,Hunter T,et al.Integrin-mediated signal transduction linked to Ras pathway by GRB-2 binding to focal adhension kinase.Nature,1994,372:22-29.
8Thannickal V J,Lee DY,White ES,et al.Myofibroblast differentiation by transforming growth factor-betal is dependent on cell adhesion and integrin signaling via focal adhesion kinase.J Biol Chem,2003,278:12384-12389.
9司徒振强,吴军正.细胞培养[M].西安:世界图书出版公司,1996:111,188.
10Zhang Y,Ikegami T,Honda A,et al.Involvement of integrin-linked kinase in carbon tetrachloride-induced hepatic fibrosis in rats.Hepatology,2006,44(3):612-622.
2Gkretsi V,Mars W,Bowen W. Loss of integrin linked kinase from mouse hepatocytes in vitro and in vivo results in apoptosis and hepatitis[J].{H}HEPATOLOGY,2007.1025-1034.
3Gagne D,Groulx JF,Benoit YD. Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism[J].{H}Journal of Cellular Physiology,2010.387-400.
4McDonald PC,Fielding AB,Dedhar S. Integrin-linked kinaseessential roles in physiology and cancer Biology[J].{H}Journal of Cell Science,2008.3121-3132.
5Cheon SS,Wei Q,Gurung A. Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing[J].FASE B J,2006.692-701.
