细支气管肺泡癌75例临床分析

Bronchioloalveolar carcinoma： clinical analysis of 7S cases

目的 总结经病理证实的75例细支气管肺泡癌（BAC）的临床特征和诊断方法.方法 对我院2001年1月～2010年6月收治的75例BAC进行回顾性分析.结果 75例BAC患者男女比例为1∶1.34,平均年龄56.9岁,吸烟者占12％; CT检查58例表现为孤立结节型,8例为弥漫结节型,9例为炎症浸润型；26例患者行CT或超声引导下经皮肺穿刺活检,22例获得确诊,9例行支气管镜检查,仅1例确诊,52例为手术后组织活检确诊.结论 BAC的临床特征不同于其他类型肺癌,CT检查有助于BAC的诊断,而经皮肺穿刺活检则能提高BAC诊断的正确率.

Objective To analyze the clinical features and diagnosis methods of 75 cases of bronchioloalveolar carcinoma （BAC） confirmed pathologically. Methods A total of 75 BAC cases from January, 2001 to June, 2010 were retrospectively analyzed. Results Among all 75 cases, the ratio of male and female was 1：1.34; the mean age was 56.5 years; the smoking patients accounted for 12%. All 75 patients had chest CT scanning. Among which, 58 patients displayed solitary tubercle, 8 patients widespread tubercles, and 9 patients infiltrating inflammation. Transthoracic biopsy guided by CT or ultrasound were performed in 26 patients, and 22 patients got definite diagnosis of BAC. Nine patients underwent bronchofibroscopy and only one got definite diagnosis. Postoperative biopsy was performed in 52 cases to get the definite diagnosis of BAC, Conclusion The clinical features of BAC are different from other lung cancers. CT scan may be beneficial in diagnosis of this disease. Transthoracic biopsy can elevate diagnosis accuracy of BAC.